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While FMF is sometimes seen in other ethnic groups, it is most common among people of Middle Eastern descent, especially those of Armenian heritage.

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Sephardic and Ashkenazi Jews, Turks, and some Arabs are also high-frequency carriers of the mutations that lead to this disorder. FMF is a recessive genetic disease, meaning that when both parents are carriers, there is a one-in-four chance of producing a child who suffers from it. An exciting development in FMF research has been the cloning of the genetic defect responsible - the MEFV gene that has been mapped to chromosome Since identification of this gene, more than 30 genetic mutations have been identified, which FMF in California now be detected through blood testing.

FMF in California

FMF is characterized by sporadic attacks of inflammation affecting the lining surfaces of body cavities. Symptoms include recurrent attacks of fever and FMF in California abdominal, chest, or joint pain usually lasting no more than three days.

These attacks can occur at varying intervals, but in between attacks, patients are usually asymptomatic. The pathogenesis of FMF is as yet unclear but relates to a self-limited dysregulation of the inflammatory response in the body inflammation running unchecked.

Often, symptoms FMF in California confused with surgical emergencies.

Colchicine, a drug used to treat gout a form of arthritisis the first-line treatment. Founded in the early s by Dr.

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Arthur Schwabe former chief of gastroenterology and Dr. Sherman Mellinkoff dean emeritus of FMF in California medical schoolthis specialty clinic is one of the largest of its kind in the Western Hemisphere, with more than registered patients.

It offers comprehensive interdisciplinary expertise with specialists ranging from medical geneticists FMF in California rheumatologists to nephrologists and immunologists Wayne Grody, MD, PhD. Besides diagnosis and treatment of FMF, another primary goal of the clinic is the education of medical Califonia, residents, and fellows; patients and their families; and the medical and lay communities at large.

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Clinical Programs. Familial Mediterranean Fever.

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